AKT1 and Familial prostate cancer: Furthermore, molecular docking and virtual screening studies identified bioactive metabolites in ALD, such as stigmasterol, isoboldine, and beta-sitosterol, with favourable ADME (Absorption, Distribution, Metabolism, and Excretion) and toxicity profiles, showing strong binding affinities to hub genes like SRC, FGFR1, and HSP90AA1 involved in prostate cancer pathways, particularly PI3K/AKT signaling (Figure 5) (Kosanam et al., 2024).