CCL20 and chronic hepatitis B virus infection: Together with the ability of CCL-20 to detect “good” levels of chronic hepatitis B (AUC = 0.751) and its excellent performance in staging disease severity (HUM = 0.387), this finding suggests that CCL-20 may be a dynamic biomarker of active inflammatory activity in chronic hepatitis B, with CCL-20 levels in chronic hepatitis B patients reflecting the severity of the active inflammatory response triggered by viral replication and helping to detect the necroinflammatory process of the disease.