Cytokines, Including Interferon-Gamma (IFN-gamma), IFN-gamma-induced protein 10 (IP-10), tumor necrosis factor (TNF), IL-1beta, IL-2, IL-4, IL-6, IL-8, IL-10, IL-12, and IL-17A, induced by SARS-CoV-2 infection, play a crucial role in the pathophysiology and progression to LC [189]. The gene discussed is TNF; the disease is laryngotracheoesophageal cleft.