Generally, one out of ten patients diagnosed with an adrenal tumor has bilateral tumor masses (the reported prevalence of bilateral adrenal incidentalomas varies between 7.5% and 15%), and the field of non-functioning adrenal tumors without clinically overt hormonal hypersecretion makes no exception (with some of these tumors being identified in patients that harbor various pathogenic variants of the ARMC5 or NR3C1 genes, etc.)[19,20,21]. Here, NR3C1 is linked to adrenal gland neoplasm.