Boxplot analysis revealed that patients with high CRP levels had significantly increased miR-129 ΔCt values (median = 10.73) compared to those with normal CRP (median = 4.58), indicating an association between elevated systemic inflammation (Figure 4), also the significant associations with CA19-9, LDH, and CRP suggest that miR-129 could serve as a bridging biomarker between metabolic inflammation and cancer progression. The gene discussed is CRP; the disease is cancer.