In the first study using CGM in individuals with identified single-nucleotide polymorphisms associated with glucose dysmetabolism, participants with the rs7903146 T-allele in the transcription factor-7-like 2 (TCF7L2) gene but without diabetes exhibited higher mean nocturnal glucose levels influenced by body composition, suggesting a potential role in hepatic glucose production [122]. Here, TCF7L2 is linked to diabetes mellitus.