At 24 h post-surgery, the systemic levels of key biomarkers in sepsis significantly increased (Figure 3B–D), including C-reactive protein (CRP), an acute phase protein responding to infection and inflammation; lactate (Lac), an indicator of tissue hypoxia and metabolic stress; and lactate dehydrogenase (LDH), a maker of cellular injury, systemic inflammation and multiorgan dysfunction. The gene discussed is CRP; the disease is Sepsis.