Bio-ADM: Bioactive adrenomedullin; CA125: Carbohydrate antigen 125; eGFR: Estimated glomerular filtration rate; HF: Heart failure; IGFBP7: Insulin-like growth factor binding protein 7; sST2: Soluble Suppression of Tumorigenicity-2; TIMP-2: Tissue inhibitor of metalloproteinases-2. The gene discussed is IGFBP7; the disease is hydrops fetalis.