This epigenetic mark exhibits a context-dependent duality: while high levels of METTL3-mediated methylation promote cell proliferation and metastasis and inhibit apoptosis in breast cancer (BC) [24], they are also implicated in non-small cell (NSCLC) and small-cell (SCLC) lung cancers. This evidence concerns the gene METTL3 and small cell lung carcinoma.