AKT1 and lung cancer: Hu Qian et al. [46] found that alidiol, brevilin A, and helenalin-isovalerate exhibited a stronger, concentration-dependent inhibitory effect on lung cancer cells within the concentration range of 2.5–20 μmol/L, and the apoptosis-inducing effect of lung cancer cells was enhanced with the increase in the concentration of the components, and found that the mechanism of their action might be related to the inhibition of p-ERK, p-AKT, and NF-κB expression of p-ERK, p-AKT and NF-κB.