FAS and infection: We found that while Fas (−) and FasL (−) mice showed significantly lower titers of HSV-1 both in the brains and TGs at 7 d p.i., AMG treatment early during infection resulted in increased titers in the brains of Fas- and FasL-deficient mice compared both to untreated controls but also to AMG-treated wild-type mice (p ≤ 0.05) (Supplementary Figure S1C).