Regarding the adaptive immune response, it is known that patients with mucormycosis caused by R. oryzae, and R. pusillus exhibit an immune profile driven by lymphocytes, macrophages, and polymorphonuclear neutrophils (PMNs), triggering responses involving IFN-γ, IL-17A, and IL-10 [40,41]. The gene discussed is IFNG; the disease is Zygomycosis.