In recent years, the analysis of the lipid abnormalities contributing to the development of atherosclerosis has focused on the rise in triglyceride (TG) contained in postprandial chylomicrons and very low-density lipoprotein (VLDL-C) cholesterol and the involvement of proteins, such as lipoprotein lipase (LPL) and hepatic triglyceride lipase (HTGL), which are important for triglyceride metabolism. Here, LPL is linked to atherosclerosis.