Based on the definition of AS-LAMP, Yongkiettrakul and her colleagues provided a proper manner for clustering the mutation points in dhfr-ts (dihydrofolate reductase of the bifunctional dihydrofolate reductase-thymidylate synthase) gene corresponding to medicine tolerance phenotypes in malaria parasites in 2017 [27]. This evidence concerns the gene DHFR and malaria.