For example, a patient with performance status (≥2), anemia, elevated LDH, high SII, positive BCL2 expression, and stage III/IV could obtain 57 points, 37 points, 52 points, 70 points, 36 points, and 100 points, respectively, resulting in a total score of 352 points. The gene discussed is BCL2; the disease is anemia (phenotype).