The variables included were maternal age, BMI, the presence of systemic disease (pre-gestational diabetes, chronic hypertension, personal history of preeclampsia and/or FGR, antiphospholipid syndrome and/or renal disease), a diagnosis of gestational diabetes during pregnancy, conception through assisted reproductive technologies, gestational weight gain, diastolic blood pressure in the third trimester, and the sFlt-1/PlGF ratio in the third trimester. The gene discussed is PGF; the disease is gestational diabetes.