Furthermore, in line with previous findings [115,116,117,118,119,120,121,122], our analysis revealed upregulation of cathepsins A, B, D, and H, while cathepsin Z upregulation and downregulation of cathepsins C, E, G, K, and V in cutaneous melanoma were not previously reported (Figure 6D), indicating that these genes merit further investigation as biomarkers and therapeutic targets in cutaneous melanoma. This evidence concerns the gene CTSZ and cutaneous melanoma.