Furthermore, in line with previous findings [115,116,117,118,119,120,121,122], our analysis revealed upregulation of cathepsins A, B, D, and H, while cathepsin Z upregulation and downregulation of cathepsins C, E, G, K, and V in cutaneous melanoma were not previously reported (Figure 6D), indicating that these genes merit further investigation as biomarkers and therapeutic targets in cutaneous melanoma. Here, CTSA is linked to cutaneous melanoma.