CRP and diabetes mellitus: Plasma TMAO was quantified by stable isotope dilution high-performance LC-MS/MS, and associations with plaque rupture were analyzed using Receiver Operating Characteristic (ROC) curves, adjusting for age, sex, smoking, triglycerides, diabetes, hypertension, high-sensitivity C-reactive protein (hs-CRP), and estimated glomerular filtration rate (eGFR).