TGFB1 and lung disorder: CIP2A expression is linked to several observations observed in pulmonary diseases, including inflammation (increased activation of NFκB, MAPKs, and pro-inflammatory cytokines), tissue remodeling (enhanced TGF-β signaling and fibroblast activation), and PP2A signaling inhibition (sustained inhibition of PP2A, resulting in the activation of oncogenic and pro-inflammatory pathways).