Without claiming to be exhaustive, these include the following cancer types: Burkitt lymphoma; glioblastoma multiforme; breast ductal carcinoma; colon, lung, and prostate adenocarcinoma; malignant melanoma; etc. The mutations in the S4 segments of Hv1 resulted in different biophysical properties in channel function [70]. Here, HVCN1 is linked to glioblastoma.