Additionally, dysregulated ClpP expression was observed in conjunction with mitotic checkpoint regulators mitotic arrest deficient 1 (MAD1L1) and end binding 1 (EB1) and stress-response proteins (HSP27, CYR61), highlighting a broader network linking mitochondrial dysfunction to chromosomal instability and resistance to apoptosis in gastric cancer. The gene discussed is MAD1L1; the disease is gastric cancer.