PCK1 and Disorder of lipid metabolism: On the other hand, the focus of mechanism research could be further expanded from PPARγ to PCK1 and Caspase-3, and the core targets of Sch B therapy for MAFLD could be screened out through network pharmacology; then, molecular docking simulations, luciferase reporter plasmid experiments, and Western blot were used to verify whether Sch B would regulate lipid metabolism disorders through PPARγ, and simultaneously, flow cytometry was used to detect its effect on cell apoptosis, so as to clarify the multidimensional regulatory role of Sch B in the pathogenesis of MAFLD.