EGFR and neoplasm: Taking into account the importance of endolysosomal pH for several stages of the lysosomal degradative pathway, the present study focused on a comparative analysis of the effect of deacidification of the endolysosomal system by the specific V-ATPase inhibitor BafA1 on the endocytic fate of EGFR in tumor-derived (HeLa and A549) and undifferentiated enMSC cell lines.