The levels of angiogenin, vascular endothelial growth factor (VEGF), soluble P-selectin (sP-selectin), and soluble receptor for advanced glycation end products (sRAGE) as well as the levels of sVCAM-1 and ICAM-1, or TNF-α and IL-18 (interleukin-18) and IL-10 (interleukin-10) were similar between group A1 and group A2 of patients with type 1 diabetes (Table 3). This evidence concerns the gene IL10 and type 1 diabetes mellitus.