In addition to its pathological role as a risk factor for Alzheimer’s disease, a homozygous mutation in the gene encoding the band 4.1, ezrin, radixin, and moesin (FERM) domain protein containing 4A (FRMD4A) is also associated with agenesis of the corpus callosum with facial anomalies and cerebellar ataxia (CCAFCA) [9]. Here, FRMD4A is linked to aceruloplasminemia.