Conversely, IL-10 functions primarily as an immunosuppressive cytokine, inhibiting proinflammatory mediators and IFN-γ expression, thereby fostering an anti-inflammatory tumor microenvironment that promotes immune escape; in human studies, elevated IL-10 levels have generally been linked to poorer prognosis, although its precise role in breast cancer progression remains unclear [101,102,103]. The gene discussed is IFNG; the disease is breast carcinoma.