OPTN and frontotemporal dementia: Recently, additional identified genetic factors of FTD were Valosin-containing protein (VCP), Charged Multivesicular Body Protein 2B (CHMP2B), TAR DNA Binding Protein (TARDBP), FUS RNA Binding Protein (FUS), Sequestosome-1 (SQSTM1), Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 10 (CHCHD10), TANK-binding kinase 1 (TBK1), optineurin (OPTN), Cyclin F (CCNF), and T-cell intracellular antigen 1 (TIA1) genes [7,8,9].