A study aimed at elucidating the possible mechanisms of cell immunity involved in HTN worked with mouse models of SS hypertension by inhibiting iNOS, with a protein overload and proteinuria, and by the infusion of Ang II, which is associated with a significant increase in the expression of HSP70 in the kidney and a significant increase in the response of T cells in lymphoid tissue [45]. Here, NOS2 is linked to hypertensive disorder.