In particular, venom from Heteroctenus junceus (previously known as Rhopalurus junceus) was shown to modulate pro-inflammatory cytokine production in F3II mouse mammary tumor cells, significantly reducing IL-6 and IL-1β while elevating TNF-α and IL-12, consistent with interference in the NF-κB pathway [191]. This evidence concerns the gene NFKB1 and breast cancer.