ACOX1 and melanoma: Furthermore, melanoma cells resistant to BRAF/MEK inhibition showed high expression of FAO genes like acyl-CoA oxidase 1 (ACOX1), short-chain acyl-CoA dehydrogenase (ACADS), CD36, carnitine palmitoyltransferase 1A (CPT1A), acyl-CoA thioesterase 8 (ACOT8), CRAT, and enoyl-CoA hydratase and 3-hydroxyacyl-CoA dehydrogenase (EHHADH) [23].