In the context of excessive mitochondrial fission and elevated levels of DRP1 and FIS1, RAB7A levels were reported as increased in different studies: in the basal forebrain, frontal cortex and hippocampus of mild cognitive impairment and AD patients, high levels of RAB7A were observed compared to controls [128,129,130]. The gene discussed is RAB7A; the disease is Cognitive impairment.