CDH17 has also been implicated in regulating EMT: Liu et al. demonstrated that its overexpression induces EMT-like changes in HCC via cyclooxygenase-2 activation, while Qu et al. showed that HOXA13-driven β-catenin expression depends on CDH17, linking it to EMT regulators [6,22]. Here, PTGS2 is linked to hepatocellular carcinoma.