IRF1 and inflammatory bowel disease: Figure 2a shows a word cloud of genes associated with CD. Prominent genes include IL23R, NOD2, ATG16L1, C1orf141, and IRF1-AS1, consistent with those identified in the broader IBD analysis, underscoring their critical roles in the disease. Notably, IL23R appears in 21 publications, making it the most significant gene, followed by NOD2 (18 publications), ATG16L1 (13 publications), C1orf141 (12 publications), and IRF1-AS1 (10 publications).