In addition, Yu Lei et al. showed that PRMT3 interacts with and mediates the ADMA modification of lactate dehydrogenase A (LDHA) at arginine 112 (R112), so PRMT3 promotes glycolysis and hepatocellular carcinoma growth by enhancing the arginine methylation of LDHA [62]. This evidence concerns the gene PRMT3 and hepatocellular carcinoma.