Additionally, hsa-miR-192-5p, hsa-miR-215-5p, hsa-miR-6845-3p, and hsa-miR-132-3p were closely associated with FTY720 treatment for NSCLC; CTBP1, EZH2, and ZNF610 all influence the expression of ZEB2 and S1PR1. The gene discussed is EZH2; the disease is non-small cell lung carcinoma.