Western blot analysis showed the up-regulation of cystathionine β-synthase, cysteine dioxygenase 1, and the transferrin receptor 1 in T98G glioblastoma cells compared to 1321N1 astrocytoma cells, while the expression of thiosulfate sulfurtransferase, cystathionine γ-lyase, 3-mercaptopyruvate sulfurtransferase, and p53 protein was comparable in both cell lines. This evidence concerns the gene TP53 and astrocytoma (excluding glioblastoma).