DDIT3 and Sepsis: In addition, in infectious diseases such as sepsis, lipopolysaccharide (LPS) induces ferroptosis in DCs, while Sestrin2 inhibits this process through the ATF4-C/EBP homologous protein (CHOP)-cation transport regulator homolog 1 (CHAC1) signaling pathway, thereby alleviating sepsis [64].