In particular, three ADE genes, which can be considered common susceptibility genes to asthma, such as glutathione-disulfide reductase (GSR), EPHX1, and GPX1, highlighted a relevant interaction in both variants of asthma in men and women (except for the GPX1 gene in nonallergic asthma in women) [66]. The gene discussed is GPX1; the disease is asthma.