Thus, both for inflammatory markers specific to atherosclerosis and associated cardiac hypertrophy (AngII, TGF-β1, MIF, ANF, CTN1, Cx43, α-SMA, COL1A, reactive oxygen species, T-cells, and macrophages) and for proteins involved in established signaling pathways (NF-kB p50), increased values were determined in the HH group compared to the control group. The gene discussed is ACTA1; the disease is atherosclerosis.