Combination of WGS and RNA-seq approaches allowed identification of several fusion genes (ESR1-CCDC170, BCL2L14-ETV6, ETV6-NTRK3, MYB-NFIB, and NOTCH/MAST kinase) that may drive BC progression and may be useful for identifying patients who need closer monitoring and more aggressive therapy [100,101]. Here, ETV6 is linked to breast cancer.