Since then, functional genomics, proteomics, and CRISPR/Cas9 studies have revealed the roles of NEKs in diverse cellular processes—from cilia maintenance (NEK1, NEK8, NEK10) to tumor progression (NEK2, NEK6, NEK11)—cementing the NEKs as essential regulators of genomic stability and cellular architecture [6,7]. The gene discussed is NEK11; the disease is neoplasm.