Histone methyltransferase EHMT2, which suppresses the expression of fumarate hydratase in nasopharyngeal carcinoma, is recruited along with EZH2 by miR-584-3p in an AGO2-dependent manner to reduce matrix metalloproteinase 14 (MMP-14) expression in gastric cancer [137]. The gene discussed is MMP14; the disease is nasopharyngeal carcinoma.