For example, a study found that minor alleles in lipid metabolism genes, such as apolipoprotein E (APOE) and hepatic lipase (LIPC), are associated with both AMD risk and with differential lipid biomarker signatures, suggesting that biomarker–genetic panels could stratify patients more effectively for antioxidant or complement-targeted therapies. This evidence concerns the gene APOE and age-related macular degeneration.