They include both dementias like AD—where tau forms hyperphosphorylated proteinaceous inclusions termed neurofibrillary tangles (NFTs)—and movement disorders such as progressive supranuclear palsy, corticobasal degeneration, or FTD with parkinsonism linked to chromosome 17 (FTDP-17) [70]. The gene discussed is MAPT; the disease is frontotemporal dementia.