KLK3 and neoplasm: Accordingly, patients with PLNI were more likely to present with higher percentages of adverse tumor grades (ISUP 4–5), PSA levels > 20 ng/mL and BPC; likewise, they were also more likely to have higher Id-BPC densities showing a stronger association (OR = 1.444; 95% CI: 1.055–1.958; p = 0.018) than BPC (OR = 1.026; 95% CI: 1.014–1.038; p < 0.0001); moreover, the cT and cN stages did not show any significant association at all.