Specifically, Deforzh et al. (2024) showed that HOXDeRNA (LINC01116) binds across the genome to the promoters of at least 35 glioma-specific transcription factors, including core stem cell regulators like SOX2, OLIG2, POU3F2, and ASCL1 [17]. This evidence concerns the gene POU3F2 and central nervous system cancer.