↓ Glucose, homeostatic model assessment of insulin resistance index, low-density lipoprotein, nesfatin-1 levels in the plasma, TNF-α, IL-1β, IL-6, Cas-3, Bcl-2-associated X protein (Bax), and inflammatory response in tissues↑ Plasma insulin, high-density lipoprotein (HDL), and tissue Bcl-2. Here, NUCB2 is linked to Insulin resistance.