Moreover, CLO inhibits growth and inhibits genes related to OS defense (thioredoxin peroxidase, glutaredoxin, nitric oxide oxidoreductase, cytochrome c peroxidase and b5 reductase, GPx, SOD1, SOD2, and CAT) in glioblastoma patient biopsy-derived cell cultures [51]. This evidence concerns the gene CAT and glioblastoma.