MSX2 and Hunter-McAlpine craniosynostosis: MSX2 mutations associated with craniosynostosis [427], complex heart defect (dextrocardia, dextroversion, PFO) cases with radial agenesis, along with other characteristics of Hunter–McAlpine syndrome (intellectual disability, craniofacial and skeletal abnormalities, and characteristic facial attributes) [223] (human)