IL6R and breast carcinoma: Supporting this, Bulska-Będkowska and colleagues [18] reported that baseline serum concentrations of the soluble IL-6 receptor (sIL-6R) and the TNF-α receptor (sTNF-R1) were significantly higher prior to surgery than at the follow-up assessment two months later (p < 0.05), reinforcing the predictive value of surgery in breast cancer.